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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Hypotensive transfusion reaction ： ウィキペディア英語版 Hypotensive transfusion reaction A Hypotensive transfusion reaction or HTR is a rare condition that presents with low blood pressure associated with administration of blood products. The low blood pressure quickly resolves when the transfusion is stopped. HTRs are caused by the production of bradykinin produced through Factor XII activation by negatively charged surfaces such as filters. When mechanisms for the degradation of bradykinin are impaired, the peptide builds up and causes hypotension. Angiotensin converting enzyme (ACE) is primarily responsible for its degradation (75%) but can be inhibited by administration of blood pressure medications called ACE inhibitors. Polymorphisms in ACE or aminopeptidase P (APP), another enzyme responsible for bradykinin degradation (20%) may also contribute to HTRs.〔http://www.medscape.com/viewarticle/543936〕 ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Hypotensive transfusion reaction」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.